Wednesday, June 21, 2017

Human genome only 90% sequenced

Were you under the impression that the human genome had been sequenced? That is was completed in 2003?

STAT reports:
“It’s very fair to say the human genome was never fully sequenced,” Craig Venter, another genomics luminary, told STAT.

“The human genome has not been completely sequenced and neither has any other mammalian genome as far as I’m aware,” said Harvard Medical School bioengineer George Church, who made key early advances in sequencing technology. ...

Perhaps nobody paid much attention because the missing sequences didn’t seem to matter. But now it appears they may play a role in conditions such as cancer and autism. ...

Church estimates 4 percent to 9 percent of the human genome hasn’t been sequenced. Miga thinks it’s 8 percent.
Why couldn't they announce that the genome was 90% sequenced? Did they think that the public was incapable of understanding that?

Of course the public can understand that. There was some sort of conspiracy to mislead the public.

I remember the original announcement making a big deal about finding all the genes, and then later learning that they did not even know how many genes there were.

I heard that there were gaps, but now I learn 4 to 9% is missing! That tells me that not only is a lot missing, but they don't even know how much is missing.

1 comment:

  1. I've programmed DNA sequencers and De Bruijn graph-based tools give up on nonresolvable repeats and yield fragmented assemblies. It's not really news.